1
Recurrent miscarriage is usually defined as having Two or more miscarriages in a row, whether or not you have had any healthy pregnancies.
Genetics: Chromosome translocation…
Abnormal Immunity: Antiphospholipid antibody syndrome…
Uterine abnormalities: endometrial adhesion or lesion…
Hormonal imbalance: TSH insufficiency…
Others: Poor DM control or PB control….
2
Prevention
Hormonal supplementation
Uterine repairment
Low-dose aspirin and heparin for immune control
Preimplantation Genetic Diagnosis or Preimplantation Genetic Diagnosis
3
Examination
- Genetics: embryotic biopsy for earlier screening
- Autoimmunity disorder : Blood taking e.g (lupus anticoagulant [LA], anticardiolipin antibodies [ACA IgG and IgM]), β2-glycoprotein I antibodies (β2-GPI), Antinuclear antibodies (ANA)…etc)
- Uterine Abnormalities: Diagnostic hysteroscopy, hysterosalpingography, MRI..etc
- Hormonal Imbalance: Blood test e.g thyroid-stimulating hormone (TSH), TPO-antibody…etc
- Other: Diabetes
4
Take the first step